Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

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Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

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Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Primate genetics: Blood typing PCR test for macaques

primate genetic test data sheet

PCR identification of A/B/AB blood type in cynomolgus and rhesus macaques

Test code:
GP100

Cynomolgus and rhesus macaques are the nonhuman primates most commonly used in biomedical research. For some research, such as transfusion and transplantation studies, it is important to know whether the blood types of donor and recipient animals are compatible.

Both cynomolgus and rhesus macaques can possess A, B or AB blood types. While it is generally thought that the O allele seen in humans does not exist in macaques, one study by Malaivijitnond et al. (2008) did report some presence of the O allele in both rhesus and cynomolgus macaque populations. However, the sample size in that study was very small and the samples were collected solely in Thailand, so the result may not be representative of other populations. The O allele has not been reported by other groups for these species.

In nonhuman primates, including rhesus and cynomolgus macaques, the A and B antigens are not present on the surfaces of red blood cells as they are in humans, but rather are found in secretions such as saliva. This lack of antigen on the surface of red blood cells prevents conventional forward typing from blood samples in these macaques, although typing can be performed using saliva samples. Reverse typing of serum or plasma may also be performed. However, both methods demand a substantial amount of fresh blood and saliva.

Blood typing by PCR, on the other hand, requires only a small amount of DNA from the animal, and the DNA can be isolated from many different sample types, including blood.

Utilities:

  • Determine blood type in cynomolgus (Macaca fascicularis) and rhesus (Macaca mulatta) macaques

References:
Malaivijitnond, S., Sae-Low, W. and Hamada, Y. (2008) The human-ABO blood groups of free-ranging long-tailed macaques (Macaca fascicularis) and parapatric rhesus macaques (M. mulatta) in Thailand. J. Med. Primatol. 37:31-37.

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or buccal swab, or 0.2 ml fresh, frozen or fixed tissue.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 3 business days

Methodology: PCR + Restriction Fragment Length Polymorphism (RFLP)

Normal range: A, B or AB blood type

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