Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

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Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Coccidioides

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

Valley fever

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

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Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Herpes papio PCR tests
primate assay data sheet

Herpesvirus papio 1 and 2 (HVP-1 and HVP-2)

Test codes:

S0052 - Qualitative detection of herpesvirus papio 1 (HVP-1) by polymerase chain reaction
S0027 - Qualitative detection of herpesvirus papio 2 (HVP-2) by polymerase chain reaction

 

Infection of baboons with herpesvirus papio 2 (HVP-2) produces a disease that is similar to human infection with herpes simplex viruses (HSV). HVP-2 infection is associated with oral and genital lesions that resemble HSV infections of humans. Male baboons develop erythema of the penis with papules or pustules that develop into small ulcerative lesions. Female baboons have been observed with ulcerative lesions on the vulvar tissues. Juvenile animals were found to have primarily oral lesions. Acquisition of genital infection is primarily associated with the onset of sexual activity in baboons. Furthermore, one study provided evidence that the virus could spontaneously reactivate from latency, a pattern consistent with HSV infection of humans.

Serological analysis has determined that over 90% of wild-caught baboons were found to have anti-HVP-2 titers, confirming that baboons are a natural host for HVP-2. However, it is not clear what percentage of them are active carriers of this virus.

Although virus isolation can be used to diagnose HVP-2 virus infection and determine carrier status, a long incubation period is required to obtain results. Viral culture also increases the potential risk of laboratory personnel contacting this virus. Furthermore, viral culture is not as sensitive or specific as PCR-based techniques. Serological testing for HVP-2 antigens is difficult because of the close antigenic relation between surface antigens among the alphaherpesviruses. HVP-2 detection by PCR is the most rapid, sensitive and specific method for the diagnosis of this infection and confirmation of the carrier status of the animal.

Utilities:

  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of HVP-1 and HVP-2
  • Early prevention of spread of these viruses among a colony
  • Minimize personnel exposure to these viruses
  • Safety monitoring of biological products and vaccines that derive from primates

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative PCR

Normal range: Nondetected

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