Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

African green monkey endogenous virus

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Coccidioides

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

Valley fever

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Adenovirus PCR test for primates

primate assay data sheet

Human adenovirus PCR screen

Test code:
S0177 - Ultrasensitive qualitative detection but not differentiation of most reported human adenoviruses by real time polymerase chain reaction

Adenoviruses, members of the family Adenoviridae, are nonenveloped viruses with an icosahedral nucleocapsid containing a double stranded DNA genome. These viruses survive well in the environment and can infect both humans and animals.

In humans, more than 50 serotypes of adenovirus have been identified. Human adenoviruses commonly infect the respiratory and GI tracts, the eye, and various other tissues. Most infections are asymptomatic, but long-term persistent infections are possible, and are a major concern to immunocompromised patients. Adenoviruses are known to be oncogenic in rodents but not in humans. They can be transmitted via direct inoculation to the conjunctiva, the fecal-oral route, aerosolized droplets, or through exposure to infected tissue or blood.

Serological diagnosis of adenoviral infection may not be suitable because of anti-adenovirus antibodies resulting from previous exposures. Culture detection of these viruses may take up to three weeks. Molecular detection by polymerase chain reaction is highly sensitive and specific, and is a useful detection method for these viruses (Al-Siyabi et al., 2013).

Utilities:

• Help confirm the disease causing agent
• Environmental monitoring
• Help ensure that animal populations are free of human adenoviruses
• Early prevention of spread of these viruses among a group of animals
• Minimize human exposure to these viruses
• Safety monitoring of biological products and vaccines that derive from susceptible animals

References:
Al-Siyabi, T., Binkhamis, K., Wilcox, M., Wong, S., Pabbaraju, K., Tellier, R. and Hatchette, T.F. (2013) A cost effective real-time PCR for the detection of adenovirus from viral swabs. Virol. J. 10:184-195.

Specimen requirements: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or 0.2 ml cerebrospinal fluid, or 0.2 ml feces or 0.2 ml urine, or rectal swab, or nasopharyngeal swab, or conjunctival swab, or 0.2 ml fresh, frozen or fixed tissue.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.
For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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