Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

* * *

Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Human varicella zoster PCR test for primates
primate assay data sheet

Human varicella-zoster virus (VZV)

Test code:
S0035 - Ultrasensitive qualitative detection of human varicella-zoster virus by real time polymerase chain reaction

 

Varicella (chickenpox) and zoster represent different clinical manifestations of infection with the same agent, varicella-zoster virus (VZV). Varicella occurs most frequently in children and is characterized by a generalized vesicular exanthem often accompanied by fever. Zoster (shingles) usually occurs in adults or immunocompromised patients (including those with AIDS) and consists of a painful, circumscribed eruption of vesicular lesions with accompanying inflammation of associated dorsal root or cranial nerve sensory ganglia. Varicella is the primary infection with VZV, whereas zoster is a secondary infection due to reactivation of latent VZV in sensory ganglia.

VZV is a member of the Herpesviridae. The genomic size is approximately 125 kb. The genome can exist in four different isomeric forms.

Nonhuman primates, such as the common marmoset, Callithrix jacchus, have been shown to be capable of being infected with human varicella-zoster virus (Provost et al., 1987). This observation is not surprising as simian varicella-zoster virus and human varicella-zoster virus share a high degree of genomic similarity and antigenicity (Felsenfeld and Schmidt, 1979; Gray and Oakes, 1984). The outbreak of human varicella virus infections in captive monkeys is of concern as the potential exists for contact between monkeys and human carriers of this virus.

Serological detection of VZV infection is not very reliable, sensitive or specific. VZV detection by PCR is the most rapid, sensitive and specific method for the diagnosis of this infection.

Utilities:

  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of VZV
  • Early prevention of spread of this virus among a colony
  • Minimize personnel exposure to this virus
  • Safety monitoring of biological products and vaccines that derive from primates

References:
Felsenfeld, A.D. and Schmidt, N.J. (1979) Varicella-zoster virus immunizes patas monkeys against simian varicella-like disease. J. Gen. Virol. 42:171-178.
Gray, W.L. and Oakes, J.E. (1984) Simian varicella virus DNA shares homology with human varicella-zoster virus DNA. Virology 136:241-246.
Provost, P.J., Keller, P.M., Banker, F.S., Keech, B.J., Klein, H.J., Lowe, R.S., Morton, D.H., Phelps, A.H., McAleer, W.J. and Ellis, R.W.(1987) Successful infection of the common marmoset (Callithrix jacchus) with human varicella-zoster virus. J. Virol. 61:2951-2955.

Specimen requirement: Lesion swab or lesion scab, or 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodologies: Qualitative real time PCR

Normal range: Nondetected

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