Respiratory symptoms got you breathless? Try our equine respiratory PCR panel -- we test for 7 respiratory bacteria and viruses from 1 swab.

Neurological symptoms got you down? Try our equine neurological PCR panel -- we test for 5 neurological diseases from 1 CSF or tissue sample.

Diarrhea got you on the run? Try our equine GI / diarrhea PCR panel -- we test for 4 GI diseases from 1 fecal or swab sample.

Oh baby! Our equine breeding PCR panel tests for 5 diseases affecting breeding success from 1 swab or semen sample.

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For our international clients: Our DRY CARDS let you mail blood samples to Zoologix easily and cheaply from anywhere. Samples are small, light and stable at room temperature for several weeks.

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Zoologix performs equine PCR tests for...

African horse sickness

Anaplasma phagocytophilum

Aspergillus

Babesia

Borrelia burgdorferi

Burkholderia mallei and pseudomallei

Clostridium difficile

Clostridium species

Contagious equine metritis (CEM)

Coronaviruses

Dourine

Eastern equine encephalitis (EEE)

E. coli O157:H7

E. coli panel

Equine adenoviruses

Equine arteritis virus (EAV)

Equine herpesvirus
type 1

Equine herpesvirus
type 2

Equine herpesvirus
type 3

Equine herpesvirus
type 4

Equine herpesvirus
type 5

Equine infectious anemia (EIA)

Equine piroplasmosis

Equine protozoal myeloencephalitis (EPM)

Giardia

Glanders

Helicobacter

Histoplasma

Horsepox virus

Influenza

Japanese encephalitis

Lawsonia intracellularis

Leptospirosis

Lyme disease

Melioidosis

Neospora caninum

Neospora hughesi

Piroplasmosis

Potomac horse fever

Rabies

Rhodococcus equi

Rotavirus

Sarcocystis neurona

St. Louis encephalitis

Strangles (Strep equi)

Streptococcus pneumoniae

Strongyles

Surra

Tapeworms

Taylorella equigenitalis

Theileria equi

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma equiperdum

Trypanosoma evansi

Venezuelan equine encephalitis (VEE)

Vesicular stomatitis

West Nile virus (WNV)

Western Equine Encephalitis (WEE)

Yersinia enterocolitica

Yersinia pseudotuberculosis

Genetic tests for...

Hyperkalemic periodic paralysis


Equine hyperkalemic periodic paralysis PCR test

equine genetic test data sheet

Equine hyperkalemic periodic paralysis

Test code: GE001 - Detection of the gene responsible for hyperkalemic periodic paralysis in horses, by polymerase chain reaction (PCR).

Hyperkalemic periodic paralysis (HYPP) is an autosomal dominant inherited disease affecting the muscle tissue of horses. It is usually caused by a point mutation in a protein that is part of the sodium channel in muscle cells. Sodium channels are "pores" in the muscle cell that regulate contraction of the muscle fibers.

Muscles of affected horses can be overly excitable and contract involuntarily. This occurs when potassium levels change in the blood, for example when fasting is followed by consumption of a high potassium feed such as alfalfa. High levels of potassium in blood (hyperkalemia) cause the muscles to contract more readily than normal, and thus affected horses will develop sporadic episodes of muscle tremors or paralysis.

Most sporadic mutations in this gene are incompatible with survival. However, one mutation, P1416L, that can be traced back through descendants of the American Quarter Horse sire Impressive (Tryon et al., 2009), produces a functional, yet altered, sodium ion channel. Because of the lesser severity of the deformation, horses with the P1416L mutation can survive but still suffer from HYPP. This gene mutation is not a product of inbreeding; the mutation inadvertently became widespread when breeders sought to produce horses with heavy musculature.

Utilities:

  • Identify the genetic cause of symptoms
  • Help confirm diagnosis of genetic disease
  • Genetic assessment for breeding control

References:
Tryon, R.C., Penedo, M.C., McCue, M.E., Valberg, S.J., Mickelson, J.R., Famula, T.R., Wagner, M.L., Jackson, M., Hamilton, M.J., Nooteboom, S. and Bannasch, D.L. (2009) Evaluation of allele frequencies of inherited disease genes in subgroups of American Quarter Horses.  J. Am. Vet. Med. Assoc. 234:120-125.

Specimen requirements: Buccal swab, or 0.1 ml EDTA whole blood.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

If there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack. See shipping instructions for more information.

Turnaround time: 3 business days

Methodology: Qualitative real time PCR

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