Top dogs can catch things too!  Our NEW dog show panel checks for 8 pathogens potentially transmissible at dog shows.

 Neuro symptoms getting on your nerves? Try our canine neurological panel - 6 neurological pathogens from 1 CSF sample; or our feline neurological panel - 5 neurological pathogens from 1 CSF sample.

Oh baby! Try our canine breeding PCR panel - 3 canine sexually transmitted diseases tested from swabs or semen samples.

Respiratory symptoms got you breathless? Try our canine respiratory PCR panel - we test for 8 canine respiratory pathogens from throat, nasal and eye swabs.

...or maybe you need our feline respiratory PCR panel -- 6 feline respiratory pathogens from throat, nasal and eye swabs.

Diarrhea got you on the run? Try our canine diarrhea PCR panel -- 8 major diarrheagenic agents from 1 fecal specimen...
...OR our 9-pathogen feline diarrhea PCR panel.

Not feeling sanguine about bloodborne pathogens in cats? Try our feline bloodborne PCR panel -- 4 major bloodborne pathogens from 1 blood sample.

Ticks bugging you? Try our tickborne disease PCR panel -- 7 major tickborne pathogens from 1 blood sample.

Just plain sick and tired? Try our canine anemia PCR panel or our feline anemia PCR panel -- detect and differentiate multiple anemia pathogens from 1 blood sample.

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Zoologix performs canine and feline PCR tests for...

Anaplasma phagocytophilum

Anaplasma platys

Aspergillus species

Aspergillus fumigatus



Baylisascaris procyonis

Bordetella bronchiseptica

Borrelia burgdorferi

Brucella canis


Canine adenovirus type 1

Canine adenovirus type 2

Canine circovirus

Canine enteric coronavirus (CCV1)

Canine distemper

Canine herpesvirus

Canine papillomavirus

Canine parainfluenza virus

Canine parvovirus

Canine pneumovirus

Canine respiratory coronavirus (CCV2)

Chagas disease

Chikungunya virus

Chlamydophila psittaci

Clostridium species




Cytauxzoon felis

Demodex gatoi mites

E. coli



Fading kitten syndrome

Feline calicivirus

Feline distemper

Feline enteric coronavirus

Feline foamy virus

Feline herpesvirus type 1

Feline immunodeficiency virus

Feline infectious anemia

Feline infectious peritonitis

Feline leukemia

Feline panleukopenia

Feline papillomavirus

Feline pneunomitis

Feline rhinotracheitis virus

Feline sarcoma virus

Feline syncytial virus

Francisella tularensis


Group G strep

Haemobartonella canis

Haemobartonella felis


Influenza type A

Lawsonia intracellularis



Lyme disease

Mange in cats


MRSA (Methicillin-resistant Staph aureus)

Mycoplasma canis

Mycoplasma cynos

Mycoplasma felis

Mycoplasma haemocanis

Mycoplasma haemofelis

Neorickettsia helmintheca

Neospora caninum

Pasteurella multocida

Pneumocystis carinii



Reovirus screen

Rickettsia screen



Salmon poisoning disease

Sarcocystis neurona

Streptococcus, Group G

Streptococcus pneumoniae

Streptococcus pyogenes

Streptococcus zooepidemicus

Toxoplasma gondii



Trypanosoma cruzi


West Nile virus

Yersinia pestis

Yersinia pseudotuberculosis

Canine respiratory coronavirus PCR test

dog and cat assay data sheet

Canine respiratory coronavirus (CCV2, CCoV2 or CRCoV)

Test code: S0134 - Ultrasensitive qualitative detection of canine respiratory coronavirus type 2 by reverse transcription coupled real time polymerase chain reaction.  This assay does not detect canine enteric coronavirus type 1.

S0134 is included on P0019 - canine respiratory panel

Canine respiratory coronavirus (CRCoV) is an RNA virus that has recently been classified as group 2 coronavirus. Sequence analysis shows that this virus is genetically related to the bovine coronavirus that causes respiratory infections in cattle and the human coronavirus that causes the "common cold" in people. However, this virus is genetically distinct from the group 1 enteric coronavirus that can cause diarrhea in dogs.
Dogs infected with CRCoV usually develop mild symptoms such as coughing, sneezing, and nasal discharge. Some infected dogs do not develop clinical signs but shed virus that can infect other dogs. These carriers are often the source of major outbreaks. Only a small number of infected dogs will develop pneumonia. From infection to disease onset may take one or two days to several weeks, depending on whether the infected dog is also co-infected with other pathogens.
CRCoV is highly contagious and is easily transmitted via the respiratory route. The likelihood of an outbreak significantly increases when large numbers of dogs are LOCATED together in close confinement, such as at boarding/training kennels, shelter facilities, dog shows and racing kennels. Dogs of all ages and breeds are susceptible to infection.
Differential diagnosis is important to differentiate CRCoV from other common pathogens that can cause similar symptoms in dogs. Diagnosis of CRCoV infection cannot be based solely on clinical signs because these are very similar to those caused by other respiratory pathogens. Antigen or culture detection of the virus in respiratory samples is low in sensitivity and specificity (Erles and Brownlie, 2005). Molecular detection using PCR is a more effective means of rapid, sensitive and specific detection of this virus.


  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of canine respiratory coronavirus infection
  • Help ensure that canine populations are free of CRCoV
  • Early prevention of spread of this virus among a canine facility or population
  • Minimize human exposure to this virus

Erles, K. and Brownlie, J. (2005) Investigation into the causes of canine infectious respiratory disease: antibody responses to canine respiratory coronavirus and canine herpesvirus in two kennelled dog populations. Arch. Virol. 150:1493-1504.

Specimen requirement: Nasal swab or throat swab.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative reverse transcription coupled real time PCR

Normal range: Nondetected

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