NEW - Neuro symptoms getting on your nerves? Try our canine neurological panel - 6 neurological pathogens from 1 CSF sample; or our feline neurological panel - 5 neurological pathogens from 1 CSF sample.

Oh baby! Try our canine breeding PCR panel - 3 canine sexually transmitted diseases tested from swabs or semen samples.

Respiratory symptoms got you breathless? Try our canine respiratory PCR panel - we test for 6 canine respiratory pathogens from throat, nasal and eye swabs.

...or maybe you need our feline respiratory PCR panel -- 6 feline respiratory pathogens from throat, nasal and eye swabs.

Diarrhea got you on the run? Try our canine diarrhea PCR panel -- 8 major diarrheagenic agents from 1 fecal specimen...
...OR our 9-pathogen feline diarrhea PCR panel.

Not feeling sanguine about bloodborne pathogens in cats? Try our feline bloodborne PCR panel -- 4 major bloodborne pathogens from 1 blood sample.

Ticks bugging you? Try our tickborne disease PCR panel -- 7 major tickborne pathogens from 1 blood sample.

Just plain sick and tired? Try our canine anemia PCR panel or our feline anemia PCR panel -- detect and differentiate multiple anemia pathogens from 1 blood sample.

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Zoologix performs canine and feline PCR tests for...

Anaplasma phagocytophilum

Anaplasma platys

Aspergillus species

Aspergillus fumigatus

Babesia

Bartonella

Baylisascaris procyonis

Bordetella bronchiseptica

Borrelia burgdorferi

Brucella

Campylobacter

Canine adenovirus type 1

Canine adenovirus type 2

Canine enteric coronavirus (CCV1)

Canine distemper

Canine herpesvirus

Canine papillomavirus

Canine parainfluenza virus

Canine parvovirus

Canine respiratory coronavirus (CCV2)

Chagas disease

Chikungunya virus

Chlamydophila psittaci

Clostridium species

Coccidia

Cryptococcus

Cryptosporidium

Cytauxzoon felis

E. coli

Ehrlichia

Fading kitten syndrome

Feline calicivirus

Feline distemper

Feline enteric coronavirus

Feline foamy virus

Feline herpesvirus type 1

Feline immunodeficiency virus

Feline infectious anemia

Feline infectious peritonitis

Feline leukemia

Feline panleukopenia

Feline papillomavirus

Feline pneunomitis

Feline rhinotracheitis virus

Feline sarcoma virus

Feline syncytial virus

Francisella tularensis

Giardia

Group G strep

Haemobartonella canis

Haemobartonella felis

Helicobacter

Influenza

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

MRSA (Methicillin-resistant Staph aureus)

Mycoplasma canis

Mycoplasma felis

Mycoplasma haemocanis

Mycoplasma haemofelis

Neospora caninum

Pasteurella multocida

Pneumocystis carinii

Rabies

Reovirus screen

Rickettsia screen

Salmonella

Sarcocystis neurona

Streptococcus, Group G

Streptococcus pneumoniae

Streptococcus pyogenes

Streptococcus zooepidemicus

Toxoplasma gondii

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tularemia

West Nile virus

Yersinia pestis

Yersinia pseudotuberculosis


Canine papillomavirus PCR test

dog and cat assay data sheet

Canine papillomavirus (CPV)

Test code:
S0197 - Ultrasensitive qualitative detection of canine papillomavirus by real time polymerase chain reaction.  This assay detects but does not differentiate CPV strains 1-8.

Papillomaviruses (PVs) are small non-enveloped DNA viruses. They are predominantly species-specific pathogens of humans and animals that can induce benign as well as malignant neoplasias in the skin and mucous membranes. Canine papillomaviruses (CPVs) are classified as lambdapapillomaviruses and are associated with papillomas, or warts, of both domestic dogs and wild canids.

Canine papillomaviruses consist of a cluster of 8 viruses designated CPV1 to CPV8. These eight viruses are characterized by distinct pathologies:

         CPV1 - focal papillomas
         CPV2 - inverted dermal papillomatosis
         CPV3 - choroid plexus pappilomas
         CPV4 (Chi) - benign pigmented plaques in pugs
         CPV5 - focal papillomas
         CPV6 - focal papillomas
         CPV7 - focal papillomas
         CPV8 (closely related to CPV4) - oral papillomatosis

Transmission of these viruses is mainly through direct contact. Infected dogs may develop benign lesions after one or two months of incubation. These benign lesions usually do not elicit any serious problems, and even severe oral papillomatosis typically shows spontaneous immune-mediated regression. However, some infected dogs do not respond to treatment, and may develop squamous cell carcinomas. Tumors can grow in any part of the body, including the face, tongue, mammary glands, vagina, cornea, interdigital pads, rectum and in post-operative skin.

Canine papillomavirus infection has been diagnosed by clinical symptoms or immunohistochemical methods. However, molecular detection by PCR is regarded as the most specific and sensitive method to confirm the diagnosis (Lange et al., 2011).

Utilities:

  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of viral infection 
  • Help ensure that dog groups and populations are free of canine papillomavirus
  • Early prevention of spread of this virus among dogs
  • Minimize human exposure to this virus
  • Safety monitoring of biological products and vaccines that derive from susceptible animals

References:
Lange, C.E., Zollinger, S., Tobler, K., Ackermann, M. and Favrot, C. (2011) Clinically Healthy Skin of Dogs Is a Potential Reservoir for Canine Papillomaviruses. J. Clin. Microbiol. 49:707-709.

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or 0.2 ml fresh, frozen or fixed tissue.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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