NEW - Neuro symptoms getting on your nerves? Try our canine neurological panel - 6 neurological pathogens from 1 CSF sample; or our feline neurological panel - 5 neurological pathogens from 1 CSF sample.

Oh baby! Try our canine breeding PCR panel - 3 canine sexually transmitted diseases tested from swabs or semen samples.

Respiratory symptoms got you breathless? Try our canine respiratory PCR panel - we test for 6 canine respiratory pathogens from throat, nasal and eye swabs.

...or maybe you need our feline respiratory PCR panel -- 6 feline respiratory pathogens from throat, nasal and eye swabs.

Diarrhea got you on the run? Try our canine diarrhea PCR panel -- 8 major diarrheagenic agents from 1 fecal specimen...
...OR our 9-pathogen feline diarrhea PCR panel.

Not feeling sanguine about bloodborne pathogens in cats? Try our feline bloodborne PCR panel -- 4 major bloodborne pathogens from 1 blood sample.

Ticks bugging you? Try our tickborne disease PCR panel -- 7 major tickborne pathogens from 1 blood sample.

Just plain sick and tired? Try our canine anemia PCR panel or our feline anemia PCR panel -- detect and differentiate multiple anemia pathogens from 1 blood sample.

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Zoologix performs canine and feline PCR tests for...

Anaplasma phagocytophilum

Anaplasma platys

Aspergillus species

Aspergillus fumigatus

Babesia

Bartonella

Baylisascaris procyonis

Bordetella bronchiseptica

Borrelia burgdorferi

Brucella

Campylobacter

Canine adenovirus type 1

Canine adenovirus type 2

Canine enteric coronavirus (CCV1)

Canine distemper

Canine herpesvirus

Canine papillomavirus

Canine parainfluenza virus

Canine parvovirus

Canine respiratory coronavirus (CCV2)

Chagas disease

Chikungunya virus

Chlamydophila psittaci

Clostridium species

Coccidia

Cryptococcus

Cryptosporidium

Cytauxzoon felis

E. coli

Ehrlichia

Fading kitten syndrome

Feline calicivirus

Feline distemper

Feline enteric coronavirus

Feline foamy virus

Feline herpesvirus type 1

Feline immunodeficiency virus

Feline infectious anemia

Feline infectious peritonitis

Feline leukemia

Feline panleukopenia

Feline papillomavirus

Feline pneunomitis

Feline rhinotracheitis virus

Feline sarcoma virus

Feline syncytial virus

Francisella tularensis

Giardia

Group G strep

Haemobartonella canis

Haemobartonella felis

Helicobacter

Influenza

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

MRSA (Methicillin-resistant Staph aureus)

Mycoplasma canis

Mycoplasma felis

Mycoplasma haemocanis

Mycoplasma haemofelis

Neospora caninum

Pasteurella multocida

Pneumocystis carinii

Rabies

Reovirus screen

Rickettsia screen

Salmonella

Sarcocystis neurona

Streptococcus, Group G

Streptococcus pneumoniae

Streptococcus pyogenes

Streptococcus zooepidemicus

Toxoplasma gondii

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tularemia

West Nile virus

Yersinia pestis

Yersinia pseudotuberculosis


Feline papillomavirus PCR test

dog and cat assay data sheet

Feline papillomavirus

Test code:
S0198 - Ultrasensitive qualitative detection of feline papillomavirus by real time polymerase chain reaction

 

Papillomaviruses (PVs) are small, non-encapsulated, epitheliotropic DNA viruses. They infect basal keratinocytes and cause benign proliferative lesions known as papillomas on the surface of cutaneous and mucosal tissues. Some strains of papillomavirus are also associated with the development of epithelial malignancies.

Papillomaviruses are species-specific. Feline papillomaviruses belong to the lambdapapillomavirus genus and consist of mucosal and cutaneous types. Papillomavirus infection of domestic cats (Felis domesticus) has been linked to a number of skin lesions, such as squamous cell carcinoma, bowenoid in-situ carcinoma, viral plaques and sarcoids.

Wild felids can also be infected with feline papillomaviruses; these viruses have been isolated from oral papillomatous lesions in the Florida panther (Puma concolor coryi; PcPV1), bobcat (Lynx rufus; LrPV1), Asian lion (Panthera leo persica; PlpPV1), snow leopard (Uncia uncia; UuPV1) and the clouded leopard (Neofelis nebulosa). Transmission of these viruses is mainly through direct contact.

Epithelial infections with papillomaviruses are rarely accompanied by inflammation. Viral infections are non-lytic. The basal lamina of the epithelium usually remains intact, effectively allowing viruses to replicate without stimulating innate or adaptive immune responses from the animals. Additionally, the viruses can escape immune attack by establishing latent persistent infections, integrating into the host cell genome, or initiating a multitude of other defense mechanisms.

Diagnosis of this viral infection is aided by examination of symptoms or immunohistochemical methods. Serology is not very sensitive because some infected animals may take 18 months or more to develop immunological responses following infection. Confirmation by polymerase chain reaction (PCR), which is highly sensitive and specific, is useful and rapid (Egberink et al., 2013).

Utilities:

  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of feline papillomavirus infection
  • Help ensure that feline groups and populations are free of feline papillomavirus
  • Early prevention of spread of this virus among a feline population
  • Minimize human exposure to this virus

References:
Egberink, H., Thiry, E., Möstl, K., Addie, D., Belák, S., Boucraut-Baralon, C., Frymus, T., Gruffydd-Jones, T., Hosie, M.J., Hartmann, K., Lloret, A., Lutz, H., Marsilio, F., Pennisi, M.G., Radford, A.D., Truyen, U., Horzinek, M.C. (2013) Feline viral papillomatosis: ABCD guidelines on prevention and management. J. Feline Med. Surg. 15:560-562.

Specimen requirement: Lesion swab or scraping, or 0.2 ml fresh, frozen or fixed tissue, or 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top) tube.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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