Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

* * *

Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Aspergillus PCR test for primates

primate assay data sheet

Aspergillus species

Test code:
F0001 - Ultrasensitive qualitative detection of Aspergillus fumigatus by real time polymerase chain reaction.

Test code: F0009 - Ultrasensitive qualitative detection but not differentiation of most common species of Aspergillus, such as Aspergillus fumigatus, A. flavus, A. terreus, A. nidulans, A. niger and others, by real time polymerase chain reaction

 

Aspergillus is a filamentous fungus that occurs ubiquitously in the environment. It is found in soil, on plants, in decaying organic matter, and in household dust and building materials. Most people inhale Aspergillus spores every day without being affected, but for immunocompromised persons such as AIDS patients and cancer patients, inhaling the fungal spores may cause illness. The spectrum of illness includes allergic reactions, lung infections, and infections in other organs.

There are more than 185 species of Aspergillus; the most common species are Aspergillus fumigatus and Aspergillus flavus. Other common species include Aspergillus terreus, Aspergillus nidulans, and Aspergillus niger.

Aspergillus infections in birds, cattle, horses, pigs, primates and other species have been reported infrequently. Pulmonary symptoms are often seen in these cases. Healthy unstressed animals are generally resistant to even high levels of spores. However, young and old animals, those on antibiotics, and those whose immune systems are suppressed by surgery, reproduction, environmental changes, capture, or shipping may become infected.

Since many animals have had prior exposure to Aspergillus, serological testing is not useful or reliable. Although traditional culture detection of Aspergillus is highly specific, culture of this organism is slow and sensitivity is low. However, molecular detection by polymerase chain reaction (PCR) is both specific and sensitive, and is a rapid and effective alternative to other methods (Buess et al., 2012).

Utilities:

  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of Aspergillus infection.
  • Help ensure that primate facilities are free of this fungus
  • Early prevention of spread of this fungus
  • Minimize personnel exposure to this fungus
  • Safety monitoring of biological products and vaccines that derive from susceptible animals

References:
Buess, M., Cathomas, G., Halter, J., Junker, L., Grendelmeier, P., Tamm, M. and Stolz, D. (2012) Aspergillus-PCR in bronchoalveolar lavage for detection of invasive pulmonary aspergillosis in immunocompromised patients. BMC Infectious Diseases 12: 237-244.

Specimen requirements: Throat or respiratory swab, or 0.2 ml water, or fungal culture, or 0.2 ml fresh, frozen or fixed tissue, or environmental surface swab.

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

 
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