Need serology?
Yes, we're still the PCR experts. But Zoologix also performs ELISA antibody tests for...

SRV
Herpes B
SIV
STLV
Measles
Hepatitis A
Hepatitis B
Hepatitis C

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Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Coccidioides

Cronobacter sakazakii

Cryptosporidium

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza

Klebsiella

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Toxoplasma gondii

Treponema pallidum

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

Valley fever

West Nile virus (WNV)

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

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Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Lyme disease PCR test for primates

primate assay data sheet

 

Lyme disease (Borrelia burgdorferi)

Test code: B0004 - Ultrasensitive qualitative detection of Borrelia burgdorferi by real time PCR. This assay detects all Borrelia genospecies within the designation Borrelia burgdorferi sensu lato, which includes those found in both North America and Eurasia.

 

Borrelia burgdorferi are gram-negative spirochete bacteria that cause Lyme disease. Spirochetes are a group of phylogenetically distinct bacteria that have a unique mode of motility by means of axial filaments (endoflagella).

Borrelia are divided into "genospecies" including B. burgdorferi sensu strict, B. garinii and B. afzelii. The term used to collectively describe all these genospecies is B. burgdorferi sensu lato. All North American isolates are genospecies B. burgdorferi sensu strict. B. garinii and B. afzelii are predominant in Europe and Asia, although all three genospecies have been found there.

B. burgdorferi invades the blood and tissues of various infected mammals and birds via the bite of ticks of genus Ixodes. The natural reservoir for B. burgdorferi is thought to be the white-footed mouse. Ticks transfer the spirochetes to deer, humans, and other warm-blooded animals after a blood meal from an infected animal. In most mammals, including humans, infection by B. burgdorferi can result in Lyme disease.

Culture detection of Borrelia is difficult because these organisms have fastidious growth requirements, and even under optimal conditions their growth is very slow. Diagnosis by serological means usually has a very low positive predictive value (Lakos et al., 2010). However, PCR is a highly specific and sensitive methodology for rapid detection of B. burgdorferi.

Utilities:

  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of Lyme disease
  • Help ensure that colonies are free of Borrelia burgdorferi
  • Early prevention of spread of Lyme disease among a facility
  • Minimize human exposure to Borrelia burgdorferi
  • Safety monitoring of biological products that derive from susceptible animals

References:
Lakos, A., Reiczigel, J. and Solymosi, N. (2010) The positive predictive value of Borrelia burgdorferi serology in the light of symptoms of patients sent to an outpatient service for tick-borne diseases. Inflamm. Res. 59:959-64.

Preferred specimen types: 0.2 ml synovial fluid or CSF, or 0.2 ml fresh, frozen or fixed tissue, or tick.

Less preferred specimen types: 0.2ml whole blood in EDTA (purple top) or ACD (yellow top) tube, or 0.2 ml urine

For specimen types other than those listed here, please call to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time polymerase chain reaction

Normal range: Nondetected

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