Simian sarcoma virus (SSV) and simian sarcoma associated virus
- Qualitative detection of simian sarcoma virus (SSV) by polymerase chain
- Qualitative detection of simian sarcoma-associated virus
(SSAV) by polymerase chain reaction
sarcoma virus (SSV) belongs to the group of mammalian type C
retroviruses and can produce tumors in primates. Originally
isolated from a fibrosarcoma in a woolly monkey, SSV is a
replication-defective v-onc virus which carries the sis oncogene.
In order to propagate, SSV requires a replication-competent
helper virus, simian sarcoma virus-associated virus (SSAV).
virus isolation can be used to diagnose SSV infection, a long
incubation period is required to obtain results. Serological
detection of SSV infection is neither sensitive nor specific. It
also increases the potential risk of laboratorians from
contacting this virus. SSV detection by PCR is the most rapid,
sensitive and specific method for the diagnosis of this
Help confirm the disease causing agent
Help ensure that animal colonies are free of SSV
Early prevention of spread of this virus among a colony
Minimize personnel exposure to this virus
Safety monitoring of biological products and vaccines
that derive from primates
Specimen requirement: 0.2 ml whole blood in EDTA (purple top) or ACD (yellow top)
types other than those listed here, please call to confirm
specimen acceptability and shipping instructions.
specimen types, if there will be a delay in shipping, or during
very warm weather, refrigerate specimens until shipped and ship
with a cold pack unless more stringent shipping requirements are
specified. Frozen specimens should be shipped so as to remain
frozen in transit. See shipping
instructions for more information.
2 business days