Zoologix performs primate infectious disease tests by PCR for...

Adenoviruses

African green monkey endogenous virus

Aspergillus

B virus

Babesia

Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi

Burkholderia

Campylobacter

Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis

Clostridium

Coccidioides

Cronobacter sakazakii

Cryptosporidium

Cynomolgus polyomavirus

Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian

Dengue

E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species

Enterovirus

Epstein-Barr virus

Giardia

Gibbon ape leukemia

Helicobacter

Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza type A

Klebsiella

Lawsonia intracellularis

Leishmania

Leptospira

Lyme disease

Lymphocryptovirus

Malaria

Measles

Monkeypox

Mycobacteria

Mycoplasma

Neisseria gonorhoeae

Neisseria meningitidis

Papillomavirus

Parvoviruses

Plasmodium species

Reovirus screen

Rhesus rhadinovirus

Rotavirus

Salmonella

Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes

SV40

SV5

Syphilis

Tetanus

Toxoplasma gondii

Treponema

Trichomonas/
Tritrichomonas

Trypanosoma cruzi

Tuberculosis

Ureaplasma

Valley fever

West Nile virus (WNV)

Yaws

Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

Zika virus

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

smCCR5Δ24
in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements


Salmonella PCR test for primates
primate assay data sheet

Salmonella

Test code:
B0040 - Qualitative ultrasensitive detection of Salmonella bacteria by real time polymerase chain reaction. This assay detects but does not differentiate most serotypes of Salmonella bacteria.

Test B0040 is included in P0041 - waterborne pathogens screening panel

Salmonella are gram negative bacteria that occur worldwide, inhabiting the intestinal tracts of many species including humans, nonhuman primates, birds, horses, pigs, dogs, cats, rats, mice, hamsters, guinea pigs and other species. The house mouse is of special concern, as it is often a carrier and plays a significant role in spreading human and animal salmonellosis.

There are more than 1600 recognized serotypes of Salmonella. Among these, S. typhimurium and S. enteritidis have been associated most commonly with lab animal colony infections. Some shipments of rhesus and cynomolgus monkeys have been found to include 20% or more Salmonella carriers.

According to a recent report (http://www.defra.gov.uk/corporate/vla/science/ documents/science-end-survrep-qtlyw405.pdf), garden bird salmonellosis is the most frequently diagnosed infectious disease among the wild birds submitted to the United Kingdom’s Diseases of Wildlife scheme. The condition is primarily caused by infection with Salmonella typhimurium, although other serotypes have been reported. Environmental contamination by these infected birds can lead to the exposure of other species, notably cats, horses and humans. Animal feed containing contaminated animal byproducts continues to be a source of Salmonella infection, especially in diets containing raw, unpelleted meal.

Humans and animals infected by Salmonella bacteria can be asymptomatic, with clinical signs precipitated by stress. Clinical infections may progress to enteritis, septicemia and variable mortality. A high percentage of survivors become carriers. In humans, acute gastroenteritis can result in sudden onset of abdominal pain, diarrhea, nausea, and fever. Septicemia may sometimes develop in humans, especially in immunocompromised patients.

Fecal and blood culture with selective media have been used to identify Salmonella. However, identification by culture has relatively low sensitivity and is quite slow. Molecular detection of these bacteria, on the other hand, is a highly sensitive and specific technique, and is also more tolerant of suboptimal specimen shipping and handling conditions.

Utilities:

  • Help confirm the disease causing agent
  • Shorten the time required to confirm a clinical diagnosis of Salmonella infection
  • Help ensure that colonies are free of these bacteria
  • Early prevention of spread of these bacteria among a colony
  • Minimize personnel exposure to these bacteria
  • Safety monitoring of biological products and vaccines that derive from primates

Specimen requirements:

Preferred specimens - rectal swab, or cloacal swab, or 0.2 ml feces or bacterial culture, or environmental swab.

Less preferred specimen - 0.2 ml whole blood in EDTA (purple top) tube.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative real time PCR

Normal range: Nondetected

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