Zoologix performs primate infectious disease tests by PCR for...


African green monkey endogenous virus


B virus


Baboon endogenous virus

Baylisascaris procyonis

Borrelia burgdorferi



Chagas' disease

Chikungunya virus

Chlamydia pneumoniae

Chlamydophila trachomatis



Cronobacter sakazakii


Cytomegalovirus, baboon

Cytomegalovirus, chimpanzee

Cytomegalovirus, human

Cytomegalovirus, macaque

Cytomegalovirus, simian


E. coli O157:H7

E. coli panel

Encephalitis, Japanese

Encephalitis, St. Louis

Encephalomyocarditis (EMCV)

Entamoeba species


Epstein-Barr virus


Gibbon ape leukemia


Hepatitis A virus

Hepatitis B virus

Hepatitis C virus

Herpes ateles

Herpes B virus

Herpes simplex type 1

Herpes simplex type 2

Herpes tamarinus

Herpesvirus ateles

Herpesvirus papio 1 & 2

Herpesvirus saimiri

Human adenoviruses

Human herpesviruses types 6, 7 & 8

Human immunodeficiency virus types 1 & 2

Human T cell lymphotropic virus

Human Varicella-Zoster

Influenza type A


Lawsonia intracellularis



Lyme disease







Neisseria gonorhoeae

Neisseria meningitidis



Plasmodium species

Reovirus screen

Rhesus rhadinovirus



Shigella and enteroinvasive E. coli

Simian agent 6 (SA6)

Simian agent 8 (SA8)

Simian foamy virus (SFV)

Simian hemorrhagic fever (SHFV)

Simian immunodeficiency virus (SIV)

Simian parainfluenza virus

Simian retrovirus (SRV)

Simian sarcoma virus

Simian T-cell leukemia (STLV) types 1 & 2

Simian T-cell leukemia (STLV) type 3

Simian Varicella-Zoster

Squirrel monkey retrovirus

Streptococcus pneumoniae

Streptococcus pyogenes





Toxoplasma gondii



Trypanosoma cruzi



Valley fever

West Nile virus (WNV)


Yellow fever

Yersinia pestis

Yersinia pseudotuberculosis

Zika virus

* * *

Genetic tests for...

A/B/AB blood type in macaques

Cynomolgus genotyping

Fetal sexing

Mamu-6 in macaques

Mamu-7 in macaques

CYP2C76 c.449TG>A
in macaques

Mu opioid receptor
in macaques

in sooty mangabeys

...and more - contact Zoologix with your genetic testing requirements

Zika virus PCR test
primate assay data sheet

Zika virus (ZIKV)

Test code:
S0227 - Ultrasensitive qualitative detection of Zikavirus by reverse transcription coupled real time polymerase chain reaction

Zika virus (ZIKV) is an enveloped single-stranded RNA virus belonging to the flaviviridae family. It is spread by the bites of Aedes mosquitoes, such as A. aegypti and A. albopictus.

There are two Zika genotypes: the African lineage and the Asian lineage. Phylogenetic studies indicate that the virus spreading in the Americas is 89% identical to African genotypes. The primary host for this virus is believed to be monkeys. In fact, the virus was first isolated in April 1947 from a rhesus macaque monkey placed in a cage in the Ziika Forest of Uganda, near Lake Victoria. Infection of humans had been considered an uncommon event until the outbreak in Micronesia during 2007 which led to more widespread research on the virus. Serological studies have now shown that a significant percentage of the human population carries neutralizing antibodies to the virus, suggesting prior exposure to the virus.

For most people, Zika viral infection is a very mild infection and is not harmful. When present, symptoms associated with the disease are non-distinctive and may include rash, itching all over the body, fever, headache, joint pain, muscle pain, conjunctivitis and lower back pain. However, the infection can be serious for pregnant women because it can cause birth defects, especially microcephaly. Babies born from infected mothers can also suffer developmental delay and mental retardation.

Serological detection of Zika virus is usually not very helpful because Zika virus cross-reacts serologically with other flaviviruses, such as dengue, West Nile, and yellow fever. Current or past infection, or even vaccination with another flavivirus, will often cause false-positive or uninterpretable Zika serology results. On the other hand, molecular detection by polymerase chain reaction (PCR) is a more useful approach to rapidly identify the virus and confirm the diagnosis (Cabral-Castro et al., 2016).


  • Help confirm the disease causing agent
  • Help ensure that animal colonies are free of this virus
  • Early prevention of spread of this virus among a colony
  • Minimize human exposure to this virus
  • Safety monitoring of biological products and vaccines that derive from primates

Cabral-Castro, M.J., Cavalcanti, M.G., Peralta, R.H.S. and Peralta, J.M. (2016) Molecular and serological techniques to detect co-circulation of DENV, ZIKV and CHIKV in suspected dengue-like syndrome patients. J. Clin. Virol. 82:108-111

Specimen requirement: 0.2 ml whole blood in EDTA (purple top) tube, or 0.2 ml serum, or 0.2 ml urine, or 0.2 ml fresh or frozen tissue.

Contact Zoologix if advice is needed to determine an appropriate specimen type for a specific diagnostic application. For specimen types not listed here, please contact Zoologix to confirm specimen acceptability and shipping instructions.

For all specimen types, if there will be a delay in shipping, or during very warm weather, refrigerate specimens until shipped and ship with a cold pack unless more stringent shipping requirements are specified. Frozen specimens should be shipped so as to remain frozen in transit. See shipping instructions for more information.

Turnaround time: 2 business days

Methodology: Qualitative reverse transcription coupled real time PCR

Normal range: Nondetected

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